Unlike fatigue caused by lack of sleep and exhaustion, fatigue that can indicate more serious illnesses, including cancer, is persistent.
Certain cancers that cause fatigue include leukemia and lymphoma, colon or stomach cancer (which can lead to slow internal bleeding and anemia), or liver cancer.
Skin Changes
Any changes in the skin should be taken seriously.
Whether it’s moles, lumps, or skin discoloration, be sure to consult your doctor.
Possible skin changes to watch out for include: moles with irregular borders or changes in color and size (likely signs of melanoma), persistent sores that don’t heal (may indicate skin cancer), yellowing of the skin and eyes (jaundice) (associated with liver or pancreatic cancer), dark spots or severe itching (may indicate cancer of internal organs).
Persistent pain
Chronic pain that doesn’t go away even after taking medication and getting enough rest.
If the pain worsens over time, you should see a doctor, as this could be a sign of a more serious condition such as bone cancer (bone pain or fractures), brain tumors (which can cause persistent headaches, nausea, and vision problems), ovarian or colon cancer (which can cause pelvic or abdominal pain), or lung cancer (chest pain).
Unusual Lumps or Swellings
Lumps and growths on the skin are not uncommon. However, if the lumps become larger, red and painful, persist for more than two weeks, are hard and immobile, or appear on your breasts or ears, you should consult your doctor.






